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Time course of histological progression in primary biliary cirrhosis

✍ Scribed by GR Locke III; TM Therneau; J Ludwig; ER Dickson; KD Lindor

Book ID: 118686097
Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 184 KB
Volume: 23
Category: Article
ISSN: 0270-9139
DOI: 10.1053/jhep.1996.v23.pm0008550048

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Time course of histological progression

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✍ G R Locke III; T M Therneau; J Ludwig; E R Dickson; K D Lindor 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 186 KB 👁 2 views

## Histological staging is used for stratification and as- A number of therapies for PBC have been investisessment of treatment efficacy in therapeutic trials for gated in clinical trials although none has been shown to primary biliary cirrhosis (PBC). Knowledge of the rate be totally effective. [

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Primary biliary cirrhosis (PBC) is a progressive cholestatic liver disease frequently leading to development of cirrhosis and its complications. Ursodeoxycholic acid (UDCA) is a beneficial medical therapy for patients with PBC. Improvement in some histological features, but not in histological stage

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Kim et al. described in the July issue of HEPATOLOGY the application of the Mayo Clinic survival model for optimal timing of liver transplantation in patients with primary biliary cirrhosis. 1 I would like to note that their application of the model for follow-up data, although widely used, is form