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Time course of hexachlorobenzene-induced alterations of lipid metabolism and their relation to porphyria

✍ Scribed by Silvia Billi de Catabbi; Norma Sterin-Speziale; María C. Fernandez; Carolina Minutolo; Carmen Aldonatti; Leonor San Martín de Viale

Book ID
117756263
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
965 KB
Volume
29
Category
Article
ISSN
1357-2725

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✍ Silvia C Billi de Catabbi; Clara P Setton-Advruj; Norma Sterin-Speziale; Leonor 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 156 KB

Hexachlorobenzene (HCB) induces porphyria both in humans and rodents, and hepatocarcinoma in rodents. In a previous work we observed that HCB produces a continuous decrease in hepatic sphingomyelin (SM) content in Wistar rats. A distinguishing characteristic of sphingolipids breakdown products is th