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Time- and Dose-dependent Induction of Invasive Urinary Bladder Cancers by N-Ethyl-N-(4-hydroxybutyl)nitrosamine in B6C3F1Mice

โœ Scribed by Tamano, Seiko ;Hagiwara, Akihiro ;Suzuki, Emako ;Okada, Masashi ;Shirai, Tomoyuki ;Fukushima, Shoji


Book ID
108579341
Publisher
Wiley (Blackwell Publishing)
Year
1991
Tongue
English
Weight
554 KB
Volume
82
Category
Article
ISSN
0910-5050

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B6D2F 1 mice (45/group) were treated with N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) or uracil as follows: Group 1 received 0.05% BBN in drinking water for the entire experiment, Group 2 received 5 mg of BBN by gastric gavage in 0.1 mL of 20% ethanol twice per week for 10 wk, Group 3 received a 2.5