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TIM-4 is the ligand for TIM-1, and the TIM-1–TIM-4 interaction regulates T cell proliferation

✍ Scribed by Meyers, Jennifer Hartt; Chakravarti, Sumone; Schlesinger, David; Illes, Zsolt; Waldner, Hanspeter; Umetsu, Sarah E; Kenny, James; Zheng, Xin Xiao; Umetsu, Dale T; DeKruyff, Rosemarie H

Book ID
109922053
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
589 KB
Volume
6
Category
Article
ISSN
1529-2908

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TIM-3 is expressed on activated human CD
TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines
✍ William D. Hastings; David E. Anderson; Nasim Kassam; Ken Koguchi; Edward A. Gre 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 545 KB

## Abstract TIM‐3 is a molecule selectively expressed on a subset of murine IFN‐γ‐secreting T helper 1 (Th1) cells but not Th2 cells, and regulates Th1 immunity and tolerance __in vivo__. At this time little is known about the role of TIM‐3 on human T cells. To determine if TIM‐3 similarly identifi