## Abstract Metformin is a major oral antiβdiabetic drug and is known as an insulin sensitizer. However, the mechanism by which metformin acts is unclear. In this study, we found that AICAR, an AMPK activator, and metformin increased the expression of Rab4 mRNA and protein levels in skeletal muscle
β¦ LIBER β¦
Tiliroside-derivatives enhance GLUT4 translocation via AMPK in muscle cells
β Scribed by Lihuan Shi; Nan Qin; Lijuan Hu; Linjuan Liu; Hongquan Duan; Wenyan Niu
- Book ID
- 116407066
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 418 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0168-8227
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Scope: Glucose uptake in skeletal muscle is crucial for glucose homeostasis. Methods and results: Insulin and muscle contraction increase glucose uptake accompanied by the translocation of glucose transporter (GLUT) 4. In a search for promising foods, which can increase glucose uptake in skeletal mu