The isothidzok 1 is not only a dipolarophile but also a reactive and versatile dienophile: especially with oxy-substituted 'donor' 1,3-butadienes, it readily combines in Diels-Alder fashion; the regiospecificity of the addition is governed by the carbonyl group of the dienophile, whereas the sulfo g
Tilcotil® Studies [3+2] additions with isothiazol-3(2H)-one 1,1-dioxide
✍ Scribed by Kaspar F. Burri
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- German
- Weight
- 802 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Regioisorneric, C(5)-halogenated derivatives were also prepared by a different method. They can be readily differentiated from the C(4)-substituted series by 'H-NMR spectroscopy. Regioselectivity of the opposite direction has been predicted for 'strongly' electron-deficient olefins [ 131.
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