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Tight Control of Matrix Metalloproteinase-1 Activity in Human Skin

✍ Scribed by Kirstin M. Südel; Kirsten Venzke; Elke Knußmann-Hartig; Ingrid Moll; Franz Stäb; Horst Wenck; Klaus-Peter Wittern; Günther Gercken; Stefan Gallinat

Book ID
111837125
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
139 KB
Volume
78
Category
Article
ISSN
0031-8655

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Remodelling of extracellular matrix (ECM) and basement membranes is a key component of the process of tumour cell invasion and metastasis. Matrix metalloproteinases (MMPs) are one of the major classes of enzymes involved in degrading ECM, having different substrate specificities and being inhibited