## Objective: To evaluate the efficacy of systemic and intraarticular adenoviral transfer of a modified tumor necrosis factor alpha receptor (tnf alphar) gene and its expression in rat collagen-induced arthritis (cia). ## Methods: Rats with cia received injections of replication-deficient adenovi
✦ LIBER ✦
Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor α–induced angiogenesis in rheumatoid arthritis
✍ Scribed by Laura M. DeBusk; Ying Chen; Toshihide Nishishita; Jin Chen; James W. Thomas; Pengnain Charles Lin
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 460 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0004-3591
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Objective. To compare the incidence of antidouble-stranded DNA (anti-dsDNA) antibodies in rheumatoid arthritis (RA) patients receiving either single or multiple doses of a chimeric anti-tumor necrosis factor ␣ (anti-TNF␣) antibody or placebo infusions, with or without methotrexate, in open-label, ra