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Tideglusib, a GSK-3 inhibitor, reduces progression of brain atrophy in progressive supranuclear palsy

✍ Scribed by Hoglinger, Gunter; Huppertz, Hans-Jürgen; Wagenpfeil, Stefan; Andrés, María; León, Teresa; del Ser, Teodoro

Book ID
122213963
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
180 KB
Volume
8
Category
Article
ISSN
1552-5260

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✍ D. M. A. Mann; R. Oliver; J. S. Snowden 📂 Article 📅 1993 🏛 Springer-Verlag 🌐 English ⚖ 717 KB

The topographic distribution of brain atrophy was quantified by image analysis of fixed coronal brain slices from 12 patients dying with Huntington's disease (HD) and from 4 other patients dying with progressive supranuclear palsy (PSP). In HD, atrophy was maximal within the caudate nucleus, putamen