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TICAM-1 and TICAM-2: toll-like receptor adapters that participate in induction of type 1 interferons

✍ Scribed by Tsukasa Seya; Hiroyuki Oshiumi; Miwa Sasai; Takashi Akazawa; Misako Matsumoto


Book ID
116306864
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
172 KB
Volume
37
Category
Article
ISSN
1357-2725

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## Abstract Toll‐like receptor 3 (TLR3) recognizes double‐stranded RNA and induces type I interferon (IFN)‐mediated antiviral immunity against a number of viral infections. Type III IFN (IFN‐λ) is a newly identified antiviral cytokine that has biological functions similar to those of type I IFNs. W