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TICAGRELOR PLASMA LEVELS BUT NOT CLINICAL OUTCOMES ARE ASSOCIATED WITH TRANSPORTER AND METABOLISM ENZYME GENETIC POLYMORPHISMS

✍ Scribed by Varenhorst, Christoph; Eriksson, Niclas; Johansson, Åsa; Barratt, Bryan; Åkerblom, Axel; Hagström, Emil; Syvänen, Ann-Christine; Becker, Richard; James, Stefan; Katus, Hugo; Husted, Steen; Steg, Gabriel; Siegbahn, Agneta; Voora, Deepak; Storey, Robert; Wallentin, Lars

Book ID: 123321306
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 233 KB
Volume: 63
Category: Article
ISSN: 1558-3597
DOI: 10.1016/S0735-1097(14)60025-5

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## Abstract In the present study, we investigated the relationship between the serotonin transporter gene linked polymorphic regions (5‐HTTLPR) or plasma paroxetine levels and clinical response to paroxetine in depressed patients. Sixty patients who met the DSM‐IV criteria for major depressive diso