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Tiagabine inhibits haloperidol-induced oral dyskinesias in rats

✍ Scribed by X. M. Gao; T. Kakigi; M. B. Friedman; C. A. Tamminga


Publisher
Springer
Year
1994
Tongue
English
Weight
442 KB
Volume
95
Category
Article
ISSN
1435-1463

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Rats received daily injections of haloperidol (HAL, 5 mg/kg SC, or IP) or tartaric acid vehicle for 14-21 days. Four to six days after discontinuation of the daily injections, rats were given a single 5-min tail pinch (TP) test. HAL-treated rats showed significantly shorter latencies to display oral