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Thyrotropin and norepinephrine stimulate the metabolism of phosphoinositides in FRTL-5 thyroid cells

✍ Scribed by Nancy J. Philp; Evelyn F. Grollman

Book ID
115918230
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
341 KB
Volume
202
Category
Article
ISSN
0014-5793

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The aim of the present study was to investigate the mechanisms regulating endothelin-1 (ET-1) secretion in rat thyroid FRTL-5 cells. ET-1 was found to be secreted after stimulation with adenosine and ATP. The release of ET-1 was sensitive to pertussis toxin, indicating a role of G-proteins in the st