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Thyroid Receptor Ligands. 6. A High Affinity “Direct Antagonist” Selective for the Thyroid Hormone Receptor

✍ Scribed by Koehler, Konrad; Gordon, Sandra; Brandt, Peter; Carlsson, Bo; Bäcksbro-Saeidi, Anna; Apelqvist, Theresa; Agback, Peter; Grover, Gary J.; Nelson, William; Grynfarb, Marlena; Färnegårdh, Mathias; Rehnmark, Stefan; Malm, Johan

Book ID
126335886
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
112 KB
Volume
49
Category
Article
ISSN
0022-2623

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Background: Thyroid hormones regulate many different physiological processes in different tissues in vertebrates. Most of the actions of thyroid hormones are mediated by the thyroid hormone receptor (TR), which is a member of the nuclear receptor superfamily of ligand-activated transcription regulat