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Thyroid-induced changes in the growth of the Liver, Kidney, and Diaphragm of Neonatal Rats

✍ Scribed by James P. Canavan; Janet Holt; Juliet Easton; Kaye Smith; David. F. Goldspink

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 714 KB
Volume: 161
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1041610107

No coin nor oath required. For personal study only.

✦ Synopsis

Eu-, hypo-and hyper-thyroid rats were studied 12 days postpartum. Hypothyroidism was induced by administering propylthiouracil (PTU) via the mother's drinking water between late gestation and throughout lactation. This procedure effectively blocked the normal early postnatal surge of T, and T, . In contrast, hyperthyroidism was induced in the young pups by daily injections of T, from day

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