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Thyroid Hormone Inhibits Growth and Stimulates Terminal Differentiation of Epiphyseal Growth Plate Chondrocytes

โœ Scribed by Yoshinori Ishikawa; Brian R. Genge; Roy E. Wuthier; Licia N. Y. Wu

Book ID
111486394
Publisher
American Society for Bone and Mineral Research
Year
1998
Tongue
English
Weight
667 KB
Volume
13
Category
Article
ISSN
0884-0431

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Thyroid hormone-mediated growth and diff
Thyroid hormone-mediated growth and differentiation of growth plate chondrocytes involves IGF-1 modulation of ฮฒ-catenin signaling
โœ Lai Wang; Yvonne Y Shao; R Tracy Ballock ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› American Society for Bone and Mineral Research ๐ŸŒ English โš– 328 KB

Thyroid hormone regulates terminal differentiation of growth plate chondrocytes in part through modulation of the Wnt/ฮฒ-catenin signaling pathway. Insulin-like growth factor 1 (IGF-1) has been described as a stabilizer of ฮฒ-catenin, and thyroid hormone is a known stimulator of IGF-1 receptor express