Leonard Wartofsky, MD, past president of the American Thyroid Association, and a panel of world-class clinicians critically review all aspects of thyroid cancer from pathogenesis to prognosis, including management and treatment. Organized for rapid access by busy physicians, the book covers both dif
Thyroid Cancer: A Comprehensive Guide to Clinical Management
β Scribed by Nikolaos Stathatos MD (auth.), Leonard Wartofsky MD, MPH, MACP, Douglas Van Nostrand MD, FACP, FACNP (eds.)
- Publisher
- Humana Press
- Year
- 2006
- Tongue
- English
- Leaves
- 680
- Edition
- 2
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
In a massive updating of the highly acclaimed Thyroid Cancer: A Comprehensive Guide to Clinical Management, Drs. Leonard Wartofsky, Douglas Van Nostrand, and an expert group of contributing authors present a wealth of new information and insights on every aspect of the etiology, pathogenesis, diagnosis, initial treatment, and long-term management of all varieties of thyroid cancer. Paramount to this new edition is a thorough treatment of the nuclear medical aspects of diagnosing and managing the thyroid cancer patient. This includes extensive discussion of isotopes, isotope uptake and scanning procedures, radioiodine ablation and dosimetry (with or without recombinant human TSH), stunning, octreotide and FDG-PET scanning, and various alternative imaging modalities. Additional highlights include management of the scan-negative and thyroglobulin-positive patient, ultrasound of the lymph nodes, local adjuncts to therapy of metastases, low iodine diets and cookbooks, future directions in therapy, and alternative therapies when traditional surgery and radioactive iodine fail.
Encyclopedic and definitive, Thyroid Cancer: A Comprehensive Guide to Clinical Management, Second Edition, offers clinical endocrinologists, nuclear medicine physicians, pathologists, oncologists, endocrine surgeons, and internists an authoritative guide to the optimal diagnosis and treatment of thyroid cancer today.
β¦ Table of Contents
Front Matter....Pages i-xxvii
Front Matter....Pages 1-1
Anatomy and Physiology of the Thyroid Gland....Pages 3-7
Epidemiology of Thyroid Cancer....Pages 9-13
Molecular Pathogenesis of Thyroid Cancer....Pages 15-32
Molecular Aspects of Thyroid Cancer in Children....Pages 33-39
Oncogenes in Thyroid Cancer....Pages 41-53
Apoptosis in Thyroid Cancer....Pages 55-61
Radiation-Induced Thyroid Cancer....Pages 63-83
Classification of Thyroid Malignancies....Pages 85-86
Staging of Thyroid Cancer....Pages 87-95
Thyroid Cancer in Children and Adolescents....Pages 97-102
Recombinant Human Thyrotropin....Pages 103-113
Front Matter....Pages 115-115
History of the Role of Nuclear Medicine in the Thyroid Gland and its Diseases....Pages 117-128
Prophylaxis Against Radiation Exposure from Radioiodine....Pages 129-132
Radioiodine Whole Body Imaging....Pages 133-150
Primer and Atlas for the Interpretation of Radioiodine Whole-Body Scintigraphy....Pages 151-178
False-Positive Radioiodine Scans in Thyroid Cancer....Pages 179-198
Front Matter....Pages 199-199
The Thyroid Nodule....Pages 201-210
Fine-Needle Aspiration....Pages 211-212
Thyroid Nodules....Pages 213-222
Radionuclide Imaging of Thyroid Nodules....Pages 223-228
Front Matter....Pages 199-199
Ultrasonic Imaging of the Neck in Patients with Thyroid Cancer....Pages 229-245
Thyroid Nodules and Cancer Risk....Pages 247-250
Front Matter....Pages 251-251
Papillary Carcinoma....Pages 253-260
Surgical Approach to Papillary Carcinoma....Pages 261-262
Papillary Carcinoma....Pages 263-270
Front Matter....Pages 271-271
Prescribed Activity for Radioiodine Ablation....Pages 273-282
Thyroid Remnant Radioiodine Ablation with Recombinant Human Thyrotropin....Pages 283-286
Front Matter....Pages 287-287
Follow-Up Strategy in Papillary Thyroid Cancer....Pages 289-292
Levothyroxine Therapy and Thyrotropin Suppression....Pages 293-296
Thyroglobulin and Thyroglobulin Antibodies....Pages 297-304
Diagnosis of Recurrent Thyroid Cancer in Patients with Antithyroglobulin Antibodies....Pages 305-308
Surveillance Radioiodine Whole-Body Scans....Pages 309-311
Radionuclide Imaging and Treatment of Thyroid Cancer in Children....Pages 313-318
Positron Emission Tomography in Well-Differentiated Thyroid Cancer....Pages 319-328
Alternative Thyroid Imaging....Pages 329-335
Stunning: Untoward Effect of 131 I Thyroid Imaging Prior to Radioablation Therapy....Pages 337-345
Stunning Is Not a Problem....Pages 346-348
Stunning: Does it Exist? A Commentary....Pages 349-350
Ultrasonic Imaging and Identification of Metastases in Cervical Lymph Nodes....Pages 351-358
Magnetic Resonance Imaging and Computed Tomography of Thyroid Cancer....Pages 359-366
Front Matter....Pages 287-287
Management of the Patients with Negative Radioiodine Scan and Elevated Serum Thyroglobulin....Pages 367-374
Determinants of Prognosis in Papillary Thyroid Cancer....Pages 375-376
Papillary Cancer....Pages 377-385
Special Presentations of Thyroid Cancer in Pregnancy, Renal Failure, Thyrotoxicosis, and Struma Ovarii....Pages 387-392
Thyroglossal Duct Carcinoma....Pages 393-395
Front Matter....Pages 397-397
Radiation and Radioactivity....Pages 399-409
Radioiodine Treatment of Distant Metastases....Pages 411-425
131 I Treatment of Metastatic Thyroid Carcinoma Following Preparation by Recombinant Human Thyrotropin....Pages 427-431
Dosimetry....Pages 433-446
Radioiodine Dosimetry with Recombinant Human Thyrotropin....Pages 447-451
Use of Lithium as an Adjuvant to Radioiodine in the Treatment of Thyroid Cancer....Pages 453-457
Side Effects of 131 I for Ablation and Treatment of Well-Differentiated Thyroid Carcinoma....Pages 459-483
External Radiation Therapy of Papillary Cancer....Pages 485-489
Chemotherapy for Thyroid Cancer....Pages 491-493
Chemotherapy of Differentiated Papillary or Follicular Thyroid Carcinoma....Pages 494-495
Thyroid Carcinoma....Pages 497-508
Adjunctive Local Approaches to Metastatic Thyroid Cancer....Pages 509-513
Front Matter....Pages 515-515
Follicular Thyroid Carcinoma....Pages 517-522
Surgical Management of Follicular Cancer....Pages 523-525
Pathology of Follicular Cancer....Pages 527-530
Front Matter....Pages 515-515
HΓΌrthle Cell Carcinoma....Pages 531-535
Radionuclide Imaging, Ablation, and Treatment in Follicular Thyroid Carcinoma....Pages 537-538
Follow-up Strategy in Follicular Thyroid Cancer....Pages 539-540
PET in Follicular Cancer, Including HΓΌrthle Cell Cancer....Pages 541-542
Follicular Thyroid Cancer....Pages 543-544
External Radiation Therapy of Follicular Carcinoma....Pages 545-548
Determinants of Prognosis in Patients With Follicular Thyroid Cancer....Pages 549-550
Front Matter....Pages 551-551
Miscellaneous and Unusual Types of Thyroid Tumors....Pages 553-569
Pathology of Miscellaneous and Unusual Cancers of the Thyroid....Pages 571-577
Front Matter....Pages 579-579
Clinical Aspects of Medullary Thyroid Carcinoma....Pages 581-589
Pathology of Medullary Thyroid Cancer....Pages 591-593
Medullary Carcinoma of the Thyroid....Pages 595-596
Radionuclide Imaging of Medullary Carcinoma....Pages 597-602
PET in Medullary Thyroid Cancer....Pages 603-604
External Radiation Therapy of Medullary Cancer....Pages 605-607
Medullary Carcinoma of the Thyroid....Pages 609-611
Front Matter....Pages 613-613
Thyroid Lymphoma....Pages 615-619
Pathology of Lymphoma of the Thyroid....Pages 621-622
FDG-PET Scanning in Lymphoma and Lymphoma of the Thyroid....Pages 623-625
Front Matter....Pages 627-627
Anaplastic Carcinoma....Pages 629-632
Front Matter....Pages 627-627
Surgical Management of Anaplastic Thyroid Carcinoma....Pages 633-634
Pathology of Anaplastic Carcinoma....Pages 635-637
PET Scanning in Anaplastic Cancer of the Thyroid....Pages 639-640
External Radiation Therapy of Anaplastic Thyroid Cancer....Pages 641-642
Chemotherapy for Anaplastic Thyroid Cancer....Pages 643-646
Anaplastic Carcinoma....Pages 647-649
Front Matter....Pages 651-651
Advances in Radiation Therapy....Pages 653-655
New Approaches in Nuclear Medicine for Thyroid Cancer....Pages 657-663
Alternative Options and Future Directions for Thyroid Cancer Therapy....Pages 665-670
Potential Approaches to Chemotherapy of Thyroid Cancer in the Future....Pages 671-674
Front Matter....Pages 675-675
Low Iodine Diets....Pages 677-681
Back Matter....Pages 683-708
β¦ Subjects
Oncology
π SIMILAR VOLUMES
This massive revision of the highly acclaimed first edition presents a wealth of new information and insights on every aspect of the etiology, pathogenesis, diagnosis, initial treatment, and long-term management of all varieties of thyroid cancer. Paramount is a thorough treatment of the nuclear med
<P>Thyroid Cancer describes all current diagnostic techniques, including FDG-PET and MRI. In recent years these modalities have documented hitherto hidden radioiodine-negative metastases, thus improving surgical therapy. The whole gamut of treatment, including surgery, radioiodine therapy, percutane
This text is an excellent, multidisciplinary resource for any physician involved in the treatment of patients with thyroid cancer. Drs. Wartofsky and Van Nostrand have assembled a diverse group of experts in pathology, endocrinology, surgery, and nuclear medicine who provide up-to-date information o