The number of glomeruli per kidney in Type 1 (insulin-dependent) and Type 2 (non-insulin-dependent) diabetic patients was estimated by an unbiased stereological method: the fractionator. No significant differences were observed between Type 1 and Type 2 diabetic patients without severe diabetic glom
Thyroid autoimmunity in Type 2 (non-insulin-dependent) diabetic patients of Caucasoid, black and Mexican origin
โ Scribed by S. Kasim; A. Bessman
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 274 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0012-186X
No coin nor oath required. For personal study only.
โฆ Synopsis
Four hundred and forty-nine patients with Type 2 (non-insulin-dependent) diabetes mellitus and 270 control subjects from Caucasoid, Mexican and black origins were screened for the presence of thyroid microsomal antibodies. Mexican female control subjects had a significantly higher frequency of thyroid microsomal antibodies when compared with black female controls (21% versus 6%, p less than 0.01). Type 2 diabetic patients did not have a higher frequency of thyroid microsomal antibodies when compared with their sex- and race-matched control counterparts. The subgroup of diabetic patients who required insulin for the control of their blood glucose did not have a higher frequency of thyroid microsomal antibodies when compared with non-insulin-requiring diabetic patients. In conclusion autoimmunity against thyroid gland, as manifested by thyroid microsomal antibodies, is not more common in Type 2 diabetic patients when compared with sex- and race-matched control subjects.
๐ SIMILAR VOLUMES
Insulin resistance is a common feature of Type 2 (non-insulin-dependent) diabetes mellitus. This defect in insulin-mediated glucose metabolism could result from a defect in either glucose oxidation or non-oxidative glucose disposal. To examine this question, euglycaemic insulin clamp studies were pe