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Thymus-independent induction of idiotype suppression in newborn mice by syngeneic anti-idiotype antisera

โœ Scribed by Georg Lehle; Eberhardt Weiler


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
806 KB
Volume
15
Category
Article
ISSN
0014-2980

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A syngeneic anti-idiotype monoclonal antibody (MAb) (CM-I I) directed against an anti-carcinoembryonic antigen (CEA) murine MAb (NP-4) was evaluated as a second antibody (SA) to promote the rapid clearance of radiolabeled NP-4 from the blood. Initial studies confirmed that CM-I I IgG removed l3Il-NP