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Thymoquinone Efficiently Inhibits the Survival of EBV-Infected B Cells and Alters EBV Gene Expression

✍ Scribed by Zihlif, M. A.; Mahmoud, I. S.; Ghanim, M. T.; Zreikat, M. S.; Alrabadi, N.; Imraish, A.; Odeh, F.; Abbas, M. A.; Ismail, S. I.

Book ID
125496006
Publisher
SAGE Publications
Year
2012
Tongue
English
Weight
791 KB
Volume
12
Category
Article
ISSN
1534-7354

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We examined the patterns of viral gene expression in acute infectious mononucleosis (IM) patients and the clonality of the directly growing EBV-carrying cell lines. Both low- and high-density EBV-carrying B cells obtained from the patients' tonsils expressed EBNA1, EBNA2 and LMP1. Like LCLs and immu