Thymidine phosphorylase expression in human colorectal mucosa, adenoma and carcinoma: Role of p53 expression
β Scribed by Kohei Shomori; Takashi Sakatani; Akira Goto; Takahiko Matsuura; Hiroshi Kiyonari; Hisao Ito
- Book ID
- 114430867
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 595 KB
- Volume
- 49
- Category
- Article
- ISSN
- 1320-5463
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## Abstract Uridine phosphorylase (UPase) and an angiogenic enzyme, thymidine phosphorylase (dThdPase) are involved in degradation of the pyrimidine nucleosides through phosphorolysis. The expression levels of UPase and dThdPase are higher in human solid tumors including breast carcinomas than in n
## Background: Thymidine phosphorylase (tp) has angiogenic activity in various cancer tissues. gastric carcinomas are classified into two histologic groups: differentiated and undifferentiated adenocarcinomas. there are differences in the modes of development and the extent of infiltration between
## Abstract Thymidine phosphorylase (TP), also known as plateletβderived endothelial cell growth factor (PDβECGF), is an enzyme that catalyzes the reversible dephosphorylation of thymidine, deoxyuridine and their analogs. TP has also angiogenic properties, although the precise mechanism by which it