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Thymidine inhibits the incorporation of 5-fluoro-2′-deoxyuridine to DNA of mouse mammary tumour

✍ Scribed by R. Nayak


Book ID
115765227
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
228 KB
Volume
184
Category
Article
ISSN
0006-291X

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Effect of 5-fluoro-2′-deoxyuridine and h
✍ Gerda Tyrsted 📂 Article 📅 1984 🏛 Springer 🌐 English ⚖ 623 KB

The inhibitors of DNA synthesis, 5-fluoro-2'-deoxyuridine and hydroxyurea, caused an inhibition of thymidine kinase, replicative DNA polymerase and CDP reductase activities in stimulated lymphocytes when they were exposed to the inhibitors during the early transformation period (0-17 hr). However, t