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Thymic stromal lymphopoietin and allergic disease

✍ Scribed by Ziegler, Steven F.

Book ID: 119286895
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 421 KB
Volume: 130
Category: Article
ISSN: 1097-6825
DOI: 10.1016/j.jaci.2012.07.010

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Thymic stromal lymphopoietin (TSLP) is an epithelial cell‐derived cytokine expressed in skin, gut, lungs, and thymus. TSLP signals via a TSLP receptor (TSLPR), a heterodimer of the IL‐7 receptor α chain and the TSLPR chain. The TSLPR chain is closely related to the common receptor γ chain that is ex