Thymic dendritic cells in culture
β Scribed by E.W.A. Kamperdijk; M. van den Berg; E.C.M. Hoefsmit
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 88 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0304-3991
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ABSTRACT Human thymic dendritic cells (DC) represent a member of the bone marrow-derived dendritic cell family. They have a dendritic shape and are found in small numbers mainly at the corticomedullary border and in medullary regions of the thymus. Human thymic DC were isolated by density gradient s
Culture of epithelial cells from the thymus of children and laboratory animals has been used for more than two decades to evaluate both the nature of these cells and their importance in the selection and maturation of functional T cells. Especially by the use of serum-free cultures and by establishm