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Thromboxane receptor blockade improves cyclosporine nephrotoxicity in rats

✍ Scribed by R.F. Spurney; S.D. Mayros; D. Collins; P. Ruiz; P.E. Klotman; T. Coffman

Book ID
119051148
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
783 KB
Volume
39
Category
Article
ISSN
0090-6980

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## Abstract Cyclosporine (CsA) causes a dose‐related decrease in renal function in experimental animals and humans. The generation of reactive oxygen species (ROS) has been implicated in CsA‐induced nephrotoxicity. It was previously shown that __Spirulina__, a blue‐green algae, with antioxidant pro