Thrombotic microangiopathy complicating pegylated interferon treatment of hepatitis C infection
β Scribed by Deena Iskander; Melissa Wickremasinghe; Barbara J. Bain
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 60 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0361-8609
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π SIMILAR VOLUMES
Randomized controlled trials of hepatitis C virus (HCV) therapy with pegylated interferon and ribavirin have demonstrated sustained viral response rates (SVRs) of 54%-63% (efficacy). Treatment results in clinical practice (effectiveness) may not be equivalent. The goal of this study was to assess th
This study was partially supported by grants UBACYT M055 (Universidad de Buenos Aires) and PICT 06-124 (Agencia Nacional de PromocioΒ΄n Cien-tΔ±Β΄fica y TecnoloΒ΄gica).
## Abstract The prevalence of occult hepatitis B, defined by absence of HBsAg and HBV DNA, ranges widely in patients with hepatitis C. This may influence the treatment of hepatitis C and the severity of liver disease. Sensitive and specific realβtime PCR techniques are available commercially and ca
Combination treatment with pegylated-interferon-alpha (PEG IFN-β£) and ribavirin, the current recommended therapy for chronic hepatitis C virus (HCV) infection, results in a sustained virological response (SVR) in only about half of patients. Because genes involved in the interferon-alpha pathway may