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Thrombospondin-2 regulates matrix mineralization in MC3T3-E1 pre-osteoblasts

✍ Scribed by Andrea I. Alford; Shawn P. Terkhorn; Anita B. Reddy; Kurt D. Hankenson

Book ID
116322592
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
874 KB
Volume
46
Category
Article
ISSN
8756-3282

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## Abstract Thrombospondin 1 (TSP1) is a multifunctional extracellular glycoprotein present mainly in the fetal and adult skeleton. Although an inhibitory effect of TSP1 against pathological mineralization in cultured vascular pericytes has been shown, its involvement in physiological mineralizatio