Thrombospondin 1 as an effective gene therapeutic strategy in collagen-induced arthritis

Effectiveness of the soluble form of the

Effectiveness of the soluble form of the interleukin-1 receptor accessory protein as an inhibitor of interleukin-1 in collagen-induced arthritis

✍ R. L. Smeets; F. A. J. van de Loo; L. A. B. Joosten; O. J. Arntz; M. B. Bennink; 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 457 KB 👁 1 views

## Abstract ## Objective To investigate whether the soluble form of interleukin‐1 (IL‐1) receptor accessory protein (sIL‐1RAcP), whose physiologic function remains to be established, can serve as a specific inhibitor of IL‐1 signaling in vitro, and to evaluate its applicability in collagen‐induced