Bone cell matrix promotes the adhesion o
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Paul J. Kostenuik; Otto Sanchez-Sweatman; F. William Orr; Gurmit Singh
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Article
📅
1996
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Springer
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English
⚖ 784 KB
Prostatic carcinoma cells have a propensity to metastasize to bone, and we propose that this phenomenon may be promoted by the adhesion of metastatic cells to bone matrix. Bone matrix is produced by osteoblasts, and we have developed an in vitro model of bone matrix by isolating the substratum depos