Hepatic thrombopoietin mRNA levels in ac
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Eva-Maria Wolber; Rainer Ganschow; Martin Burdelski; Wolfgang Jelkmann
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Article
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1999
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John Wiley and Sons
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English
⚖ 73 KB
The liver is the main production site of the hormone thrombopoietin (TPO), the major regulator of megakaryopoiesis. To investigate the role of an impaired TPO gene expression in the pathogenesis of thrombocytopenia in pediatric patients suffering from liver failure, we measured hepatic TPO mRNA in c