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Thrombocytopenia: a complication of Kawasaki disease

✍ Scribed by T. Hara; Y. Mizuno; H. Akeda; J. Fukushige; K. Ueda; T. Aoki; H. Sunagawa; S. Honda; T. Hijii; Y. Yamaguchi; T. Hosoyamada

Publisher: Springer
Year: 1988
Tongue: English
Weight: 279 KB
Volume: 147
Category: Article
ISSN: 0340-6997
DOI: 10.1007/bf00442611

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✦ Synopsis

Thrombocytopenia was observed in 10 (2.0%) of 486 children with Kawasaki disease. In nine of the ten, the minimal paltelet count of 94000 _ 38000 (SD)/mm 3 was seen on day 6.8 -2.2 (SD) of illness and the platelet counts were elevated to the normal level in 1-2 weeks. Thrombocytopenia in the nine appeared to be caused via coagulation-mediated platelet consumption, while the remaining child was diagnosed as having idiopathic thrombocytopenic purpura. One of the two who had severe coagulation-mediated thrombocytopenia of less than 50000/ram 3 developed coronary aneurysms persisting over i year.

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