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Thrombin/thrombin receptor (PAR-1)-mediated induction of IL-8 and VEGF expression in prostate cancer cells

✍ Scribed by Jian Liu; Peter Schuff-Werner; Michael Steiner

Book ID: 116292501
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 389 KB
Volume: 343
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2006.02.136

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## Abstract We previously reported that expression of angiogenesis factors interleukin‐8 (IL‐8) and vascular endothelial growth factor (VEGF) is promoted by coactivation of transcription factors nuclear factor‐kappaB (NF‐κB) and activator protein‐1 (AP‐1) by interleukin‐1α in human head and neck sq