Thrombin-stimulated cell division involves proteolysis of its cell surface receptor
โ Scribed by Glenn, Kevin C.; Cunningham, Dennis D.
- Book ID
- 109713723
- Publisher
- Nature Publishing Group
- Year
- 1979
- Tongue
- English
- Weight
- 543 KB
- Volume
- 278
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/278711a0
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
When 125I-thrombin was incubated with foreskin fibroblasts, cervical carcinoma cells or fibrosarcoma cells of human origin, or with secondary chick embryo cells or Chinese hamster lung cells, it became directly linked to its cell surface receptors. The thrombin-receptor complex (TH-R) was derived ex
To delineate the role of binding of urokinase type plasminogen activator (uPA) to its receptor (uPAR) in the local generation of plasmin by endothelium, we transfected spontaneously transformed immortalized human vascular endothelial cells that express high levels of uPA but low levels of uPAR with
We have studied the process of transferrin endocytosis in human erythromyeloid cell line K562 using fluorescein (FL) and rhodamine (RD) labeled iron-saturated transferrin (FeTF), and a fluorescein labeled monoclonal antibody to the transferrin receptor (FL-mAB). Because the antireceptor antibody and