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Thrombin promotes proinflammatory phenotype in human vascular smooth muscle cell

✍ Scribed by Sung-Woon Chung; Jae-Woo Park; Sae-A Lee; Seong-Kug Eo; Koanhoi Kim


Book ID
116300294
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
632 KB
Volume
396
Category
Article
ISSN
0006-291X

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## Abstract Hyaluronan (HA) accumulates in vascular disease but its functional role is not fully understood. To investigate the impact of HA enriched extracellular matrices (ECM) on cell phenotype, arterial smooth muscle cells (ASMCs) were transduced with retroviral constructs (LXSN) encoding murin