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Thrombin and Factor Xa Enhance Neutrophil Chemoattractant Production after Ischemia/Reperfusion in the Rat Liver

✍ Scribed by Yasuo Yamaguchi; Kazutoshi Okabe; Jian Liang; Hajime Ohshiro; Kohjiroh Ishihara; Shinichiro Uchino; Jia-Lin Zhang; Hideki Hidaka; Shinwa Yamada; Michio Ogawa


Book ID
115636138
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
125 KB
Volume
92
Category
Article
ISSN
0022-4804

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Pretreatment with activated protein C or
✍ Y Yamaguchi; N Hisama; K Okajima; M Uchiba; K Murakami; Y Takahashi; S Yamada; K πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 271 KB πŸ‘ 2 views

We investigated the role of anticoagulant in the ischemia/reperfusion injury of the liver, using activated protein C (APC), active human urinary thrombomodulin (UTM), and factor Xa blocked at the active site (DEGR-Xa). Liver ischemia was induced in male Wistar rats by occlusion of the portal vein wi