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Three New Arylnaphthalide Lignans from the Aerial Parts of Bupleurum marginatumWall. ex DC.

✍ Scribed by Ying Liu; Ting-Ting Zhang; Jin-Song Zhou; Qiang Wang

Publisher
John Wiley and Sons
Year
2008
Tongue
German
Weight
175 KB
Volume
91
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Three new arylnaphthalide lignans, 5‐(4‐hydroxy‐3‐methoxyphenyl)furo[3′,4′: 6,7]naphtho[2,3‐d]‐1,3‐dioxol‐6(8__H__)‐one (1), 10‐(4‐hydroxy‐3‐methoxyphenyl)furo[3′,4′: 6,7]naphtho[1,2‐d]‐1,3‐dioxol‐9(7__H__)‐one (2), and 10‐(3,4‐dimethoxyphenyl)‐6‐hydroxyfuro[3′,4′: 6,7]naphtho[1,2‐d]‐1,3‐dioxol‐9(7__H__)‐one (3), together with two known ones, chinensin (4) and isodiphyllin (5), were isolated from the aerial parts of Bupleurum marginatum Wall. ex DC. The structures of the three new lignans were established by means of NMR spectroscopic studies, including HQSC, HMBC, and ROESY.

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