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Three-layer guar gum matrix tablet formulations for oral controlled delivery of highly soluble trimetazidine dihydrochloride

โœ Scribed by Y.S.R. Krishnaiah; R.S. Karthikeyan; V. Gouri Sankar; V. Satyanarayana


Book ID
114161606
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
140 KB
Volume
81
Category
Article
ISSN
0168-3659

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Bioavailability studies on guar gum-base
โœ Y.S.R Krishnaiah; R.S Karthikeyan; P Bhaskar; V Satyanarayana ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 172 KB

Guar gum-based three-layer matrix tablets of a highly water-soluble drug, trimetazidine dihydrochloride, were evaluated for their in vivo release in healthy volunteers in comparison with commercially available conventional immediate release tablets. Six healthy volunteers participated in the study a