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Three dose induction regimen of infliximab (Remicade) is superior to a single dose in patients with Crohns disease (CD)

✍ Scribed by Lloyd Mayer; Chenlong Han; Mohan Bala; Greg Keenan; Allan Olson; Stephen B Hanauer; Paul J Rutgeerts


Book ID
119391847
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
30 KB
Volume
96
Category
Article
ISSN
0002-9270

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Background: NI-0401 is a fully human monoclonal antibody, which binds to the CD3 subunit of the T-cell receptor, causing modulation of T-cell activity. We investigated the safety and the ability to modulate the TCR-CD3 complex of NI-0401 in patients with active Crohn's disease (CD). Methods: A doub