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Three distinct roles of aquaporin-4 in brain function revealed by knockout mice

✍ Scribed by A.S. Verkman; Devin K. Binder; Orin Bloch; Kurtis Auguste; Marios C. Papadopoulos

Book ID
116274171
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
668 KB
Volume
1758
Category
Article
ISSN
0005-2736

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Aquaporin-4 (AQP4), a predominant water channel of the brain, mediates transmembrane water movement at the blood-brain barrier and brain-cerebrospinal fluid interface. A broad pattern of evidence indicates that AQP4 and regulators of its expression are potential targets for treatment of brain swelli