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Three-Dimensional Structure of the S4–S5 Segment of the Shaker Potassium Channel

✍ Scribed by Ohlenschläger, Oliver; Hojo, Hironobu; Ramachandran, Ramadurai; Görlach, Matthias; Haris, Parvez I.


Book ID
118515103
Publisher
Biophysical Society
Year
2002
Tongue
English
Weight
291 KB
Volume
82
Category
Article
ISSN
0006-3495

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The solution structure of the S4–S5 link
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The human ether‐à‐go‐go related gene (hERG) encodes a protein that forms a voltage‐gated potassium channel and plays an important role in the heart by controlling the rapid delayed rectifier K^+^ current (__I__~Kr~). The S4–S5 linker was shown to be important for the gating of the hERG channel. Nucl