𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Three-dimensional structure of a human pancreatic ribonuclease variant, a step forward in the design of cytotoxic ribonucleases

✍ Scribed by J Pous; A Canals; S.S Terzyan; A Guasch; A Benito; M Ribó; M Vilanova; M Coll

Book ID
115630836
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
525 KB
Volume
303
Category
Article
ISSN
0022-2836

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Structural features for the mechanism of
Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant
✍ Antonello Merlino; Giovanna Avella; Sonia Di Gaetano; Angela Arciello; Renata Pi 📂 Article 📅 2008 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 210 KB

## Abstract A specialized class of RNases shows a high cytotoxicity toward tumor cell lines, which is critically dependent on their ability to reach the cytosol and to evade the action of the ribonuclease inhibitor (RI). The cytotoxicity and antitumor activity of bovine seminal ribonuclease (BSRNas