Without a crystallized structure for a human cytochrome P450, the use of computational molecular modeling is one approach to examine the active site requirements of substrate and inhibitor specificity. CYP2D6 is undoubtedly the most studied polymorphic human CYP and it is therefore desirable for dru
Three-dimensional structural databases developed for quantitative structure—activity relationships studies
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 113 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0169-7439
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