✦ LIBER ✦

Three-dimensional reconstruction of the cochlea from two-dimensional images of optical sections

✍ Scribed by Arne H. Voie; Francis A. Spelman

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 815 KB
Volume: 19
Category: Article
ISSN: 0895-6111
DOI: 10.1016/0895-6111(95)00034-8

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✦ Synopsis

This paper describes a methodology for three-dimensional (3D) computer-aided reconstruction of the guinea pig cochlea using orthogonal-plane fluorescence optical sectioning. Specimens are sectioned optically, allowing them to remain intact during observation. Equations to correct the data for specimen translation and rotation are developed and 3D reconstructions of the scala tympani, round window membrane, and cochlear aqueduct are presented. The error associated with the reconstruction is estimated to be < 19 microns.

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