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Three-Dimensional Quantitative Structure−Activity Relationship of 1,4-Dihydropyridines As Antitubercular Agents

✍ Scribed by Kharkar, Prashant S.; Desai, Bhavik; Gaveria, Harsukh; Varu, Bharat; Loriya, Rajesh; Naliapara, Yogesh; Shah, Anamik; Kulkarni, Vithal M.

Book ID: 127311679
Publisher: American Chemical Society
Year: 2002
Tongue: English
Weight: 456 KB
Volume: 45
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm020217z

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## Abstract The three‐dimensional quantitative structure‐activity relationships of a series of 5‐[1‐aryl‐1,4‐dihydro‐6‐methylpyridazin‐4‐one‐3‐yl]‐2‐arylamino‐1,3,4‐thiadiazoles, related to the fungicidal activity, were studied using the comparative molecular field analysis (CoMFA). The results sho