Three-dimensional homonuclear TOCSY-NOESY of nucleic acids. Possibilities for improved assignments

Assignment Strategies and Analysis of Cr

Assignment Strategies and Analysis of Cross-Peak Patterns and Intensities in the Three-Dimensional Homonuclear TOCSY-NOESY of RNA

✍ S.S. Wijmenga; H.A. Heus; B. Werten; G.A. Vandermarel; J.H. Vanboom; C.W. Hilber 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 755 KB

The application of 3D TOCSY-NOESY to the analysis of RNA is presented, using a TOCSY-NOESY spectrum of the RNA duplex \(r\left(5^{\prime} G G G C U G A A G C C U^{\prime}\right)\). It is shown that for RNA molecules, 3D spectra can be obtained with a digital resolution comparable to that obtained fo