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Three-dimensional engineered heart tissue from neonatal rat cardiac myocytes

โœ Scribed by Zimmermann, Wolfram H. (author);Fink, Christine (author);Kralisch, Dirk (author);Remmers, Ute (author);Weil, Joachim (author);Eschenhagen, Thomas (author)


Publisher
John Wiley and Sons Inc.
Year
2000
Tongue
English
Weight
704 KB
Volume
68
Category
Article
ISSN
0006-3592

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Three-dimensional engineered heart tissu
โœ Zimmermann, Wolfram H. (author);Fink, Christine (author);Kralisch, Dirk (author) ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons Inc. ๐ŸŒ English โš– 704 KB

A technique is presented that allows neonatal rat cardiac myocytes to form spontaneously and coherently beating 3-dimensional engineered heart tissue (EHT) in vitro, either as a plane biconcaval matrix anchored at both sides on Velcro-coated silicone tubes or as a ring. Contractile activity was moni