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Three-dimensional 87Rb NMR imaging and spectroscopy of K+ fluxes in normal and postischemic pig hearts

โœ Scribed by V.V. Kupriyanov; B. Xiang; J. Sun; G. Dai; O. Jilkina; V. Dao; R. Deslauriers


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
249 KB
Volume
44
Category
Article
ISSN
0740-3194

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An experimental model was developed to evaluate the effects of activators and inhibitors of K(ATP) channels on unidirectional K+ fluxes in the whole heart. Isolated rat hearts perfused in the Langendorff mode were equilibrated with Pi-free Krebs-Henseleit buffer (KH buffer) containing 0.94-2.14 mM R