Three dimensional (3D) analysis of the morphological changes induced by 50 Hz magnetic field exposure on human lymphoblastoid cells (Raji)
✍ Scribed by A. Lisi; D. Pozzi; E. Pasquali; S. Rieti; M. Girasole; A. Cricenti; R. Generosi; A.L. Serafino; A. Congiu-Castellano; G. Ravagnan; L. Giuliani; S. Grimaldi
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 135 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0197-8462
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✦ Synopsis
Human Raji B lymphoid cells after exposure for 64 h to a 1 mT (rms) 50 Hz sinusoidal magnetic field showed a reorganization of membrane and cytoskeletal components. Atomic force microscopy in air revealed several modifications in 80% of the exposed cells, such as loss of microvilli-like structures followed by progressive appearance of membrane introflections. This change in plasma membrane morphology was also accompanied by a different actin distribution, as detected by phalloidin fluorescence. These observations support our previous hypothesis that electric and magnetic fields may modify the plasma membrane structure. Bioelectromagnetics 21:46±51, 2000.