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Three-Component Reaction of Triphenylphosphine, Dialkyl Acetylenedicarboxylate, and 2-Aminothiazole or 2-Aminobenzothiazole in the Presence of Arylglyoxals: An Efficient One-Pot Synthesis of Highly Functionalized Pyrroles

✍ Scribed by Anary-Abbasinejad, Mohammad; Farashah, Hamidreza Dehghanpour; Hassanabadi, Alireza; Anaraki-Ardakani, Hossein; Shams, Nasim


Book ID
120801520
Publisher
Taylor and Francis Group
Year
2012
Tongue
English
Weight
274 KB
Volume
42
Category
Article
ISSN
0039-7911

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## Abstract An effective route to functionalized 2__H__‐chromene (=2__H__‐1‐benzopyran) derivatives 4 is described (__Schemeβ€…1__). This involves the reaction of a 1,1‐diactivated alkene, resulting from the reaction of dimedone (=5,5‐dimethylcyclohexane‐1,3‐dione; 1a) with methyl chloroglyoxylate (C