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Three-Component Enantioselective Synthesis of Propargylamines through Zr-Catalyzed Additions of Alkyl Zinc Reagents to Alkynylimines

✍ Scribed by Laura C. Akullian; Marc L. Snapper; Amir H. Hoveyda

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
141 KB
Volume
42
Category
Article
ISSN
0044-8249

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πŸ“œ SIMILAR VOLUMES

Practical Highly Enantioselective Synthe
Practical Highly Enantioselective Synthesis of Propargylamines through a Copper-Catalyzed One-Pot Three-Component Condensation Reaction
✍ Nina Gommermann; Paul Knochel πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 277 KB πŸ‘ 2 views

## Abstract The one‐pot three‐component reaction of terminal alkynes, aldehydes and secondary amines in the presence of copper(I) bromide/quinap is reported. The reaction scope has been determined and a broad variety of all three components has been used, which afforded the corresponding propargyla